TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis

202245 citationsReviewhybrid Open Access

Authors

J. Osinga · Erasmus MC

Arash Derakhshan · Erasmus MC

Glenn E. Palomaki · Brown University

Ghalia Ashoor · Harris Birthright Research Centre for Fetal Medicine

Tuija Männistö · Oulu University Hospital

Spyridoula Maraka · Central Arkansas Veterans Healthcare System

Liangmiao Chen

Abstract

We provide an overview of clinically relevant reference intervals for TSH and FT4 in pregnancy. The results of the meta-analysis indicate that future studies can adopt a simplified study setup without additional exclusion criteria.

Topics & Keywords

Thyroid Disorders and Treatments Growth Hormone and Insulin-like Growth Factors Sexual Differentiation and Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 107, Issue 10, pp. 2925-2933

DOI: 10.1210/clinem/dgac425

Field-Weighted Citation Impact: 5.73