Implementing greening into design in analytical chemistry

From the pharmaceutical industry is known the approach Quality-by-Design (QbD) and this has great influence on analytical methods and procedures it employs. There is even proposed “analytical quality-by-design” to emphasise the role of analytical chemistry in quality control system of this industry. However, every branch of chemical industry in principle has the quality system where big part is related to chemical analysis and respective quality control system. By time more green chemistry principles like minimising the generation of waste and reducing the use of materials and energy as well as including analytical measurements in large-scale quality-control processes, are integrated into production of chemicals. The integration of green chemistry principles in analytical chemistry will bring these principles also into QbD of particular industry. In present work the review of examples is given on introduction of green analytical methods into QbD.