A polygenic risk score predicts atrial fibrillation in cardiovascular disease

202272 citationsJournal Articlegreen Open Access

Authors

Nicholas Marston · Brigham and Women's Hospital

Amanda C. Garfinkel · Brigham and Women's Hospital

Frederick Kamanu · Brigham and Women's Hospital

Giorgio Melloni · Brigham and Women's Hospital

Carolina Roselli · Broad Institute

Petr Jarolı́m · Brigham and Women's Hospital

David D. Berg

Abstract

In patients with cardiovascular conditions, AF PRS is a strong independent predictor of incident AF that provides complementary predictive value when added to a validated clinical risk score and NT-proBNP.

Topics & Keywords

Atrial Fibrillation Management and Outcomes Lipoproteins and Cardiovascular Health Cardiovascular Function and Risk Factors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Heart Journal

Volume 44, Issue 3, pp. 221-231

DOI: 10.1093/eurheartj/ehac460

Field-Weighted Citation Impact: 10.83