Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

2022109 citationsJournal Articlegold Open Access

Authors

Isabel Huber‐Ruano · Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas

Enrique Calvo · Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas

Jordi Mayneris‐Perxachs · Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition

M‐Mar Rodríguez‐Peña · Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas

Victòria Ceperuelo‐Mallafré · Universidad Rovira i Virgili

Lídia Cedó · Institut d'Investigació Sanitària Pere Virgili

Abstract

Overall, our work uncovers O. laneus as a promising next-generation probiotic to deplete succinate and improve glucose tolerance and obesity-related inflammation. Video Abstract.

Topics & Keywords

Gut microbiota and health Tryptophan and brain disorders Diet and metabolism studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Microbiome

Volume 10, Issue 1, pp. 135-135

DOI: 10.1186/s40168-022-01306-y

Field-Weighted Citation Impact: 9.10