CTCF and cohesin promote focal detachment of DNA from the nuclear lamina

202229 citationsJournal Articlegold Open Access

Authors

Tom van Schaik · The Netherlands Cancer Institute

Ning Qing Liu · Oncode Institute

Stefano Giustino Manzo · The Netherlands Cancer Institute

Daan Peric‐Hupkes · Oncode Institute

Elzo de Wit · Oncode Institute

Bas van Steensel · Erasmus MC

Abstract

These findings illustrate that CTCF and cohesin are not primary determinants of LAD patterns. Rather, these proteins locally modulate NL interactions.

Topics & Keywords

Genomics and Chromatin Dynamics RNA Research and Splicing Nuclear Structure and Function

Publication Details

Published in: Genome biology

Volume 23, Issue 1, pp. 185-185

DOI: 10.1186/s13059-022-02754-3

Field-Weighted Citation Impact: 2.34

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CTCF and cohesin promote focal detachment of DNA from the nuclear lamina

Authors

Abstract

Topics & Keywords

Publication Details