Efficacy of ketamine intervention to decrease alcohol use, cravings, and withdrawal symptoms in adults with problematic alcohol use or alcohol use disorder: A systematic review and comprehensive analysis of mechanism of actions.

202231 citationsReviewhybrid Open Access

Authors

Nicolas Garel · McGill University

Christina McAnulty · Université de Montréal

Kyle T. Greenway · McGill University

Paul Lespérance · Université de Montréal

Jean‐Philippe Miron · Université de Montréal

Soham Rej · Jewish General Hospital

Stéphane Richard‐Devantoy ·

Abstract

Despite promising results, the current evidence does not permit definitive conclusions about the efficacy of ketamine in alcohol use disorders or withdrawal. Future studies are warranted.

Topics & Keywords

Alcoholism and Thiamine Deficiency Treatment of Major Depression Tryptophan and brain disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Drug and Alcohol Dependence

Volume 239, pp. 109606-109606

DOI: 10.1016/j.drugalcdep.2022.109606

Field-Weighted Citation Impact: 3.49