Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode

2022129 citationsReviewgreen Open Access

Authors

Taeho Greg Rhee · Yale University

Sung Ryul Shim · Kyungnam University

Brent P. Forester · Harvard University

Andrew A. Nierenberg · Harvard University

Roger S. McIntyre · Brain and Cognition Discovery Foundation

George I. Papakostas · Harvard University

John H. Krystal ·

Abstract

Findings from this systematic review and meta-analysis suggest that ECT may be superior to ketamine for improving depression severity in the acute phase, but treatment options should be individualized and patient-centered.

Topics & Keywords

Treatment of Major Depression Electroconvulsive Therapy Studies Bipolar Disorder and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Psychiatry

Volume 79, Issue 12, pp. 1162-1162

DOI: 10.1001/jamapsychiatry.2022.3352

Field-Weighted Citation Impact: 20.57