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Using human genetics to improve safety assessment of therapeutics | Researchclopedia

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Using human genetics to improve safety assessment of therapeutics

202283 citationsReview

Authors

Keren Carss · AstraZeneca (United Kingdom)

Aimée M. Deaton · Amgen (United States)

Alberto Del Río-Espínola · Novartis (Switzerland)

Dorothée Diogo · Takeda (United States)

Mark R. Fielden · Amgen (United States)

Diptee Kulkarni · GlaxoSmithKline (United States)

Jonathan G. Moggs

Topics & Keywords

Pharmaceutical studies and practices CRISPR and Genetic Engineering Genomics and Rare Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature Reviews Drug Discovery

Volume 22, Issue 2, pp. 145-162

DOI: 10.1038/s41573-022-00561-w

Field-Weighted Citation Impact: 31.21

· Novartis (Switzerland)

Peter Newham · AstraZeneca (United Kingdom)

Matthew R. Nelson · Deerfield (United States)

Frank D. Sistare · United States Military Academy

Lucas D. Ward · Amgen (United States)

Jing Yuan · Amgen (United States)