Early detection and prognosis prediction for colorectal cancer by circulating tumour DNA methylation haplotypes: a multicentre cohort study

202280 citationsJournal Articlegold Open Access

Authors

Shaobo Mo · Shanghai Medical College of Fudan University

Weixing Dai · Shanghai Medical College of Fudan University

Hui Wang · Sinotech Genomics (China)

Xiao-Liang Lan · Nanfang Hospital

Chengcheng Ma · Sinotech Genomics (China)

Zhixi Su · Sinotech Genomics (China)

Wenqiang Xiang

Abstract

Background Early detection and prognosis prediction of colorectal cancer (CRC) can significantly reduce CRC-related mortality. Recently, circulating tumour DNA (ctDNA) methylation has shown good application foreground in the early detection and prognosis prediction of multiple tumours.

Topics & Keywords

Cancer Genomics and Diagnostics Genetic factors in colorectal cancer Colorectal Cancer Screening and Detection

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: EClinicalMedicine

Volume 55, pp. 101717-101717

DOI: 10.1016/j.eclinm.2022.101717

Field-Weighted Citation Impact: 7.12