Mechanism of Sijunzi Decoction in the treatment of colorectal cancer based on network pharmacology and experimental validation

2022257 citationsJournal Articlehybrid Open Access

Authors

Luorui Shang · Union Hospital

Yichong Wang · Capital Medical University

Jinxiao Li · Union Hospital

Fangyuan Zhou · Union Hospital

Kunmin Xiao · Beijing University of Chinese Medicine

Yuhan Liu · Integrated Chinese Medicine (China)

Mengqi Zhang ·

Abstract

SJZD can treat CRC through multiple components, multiple targets and multiple pathways. We initially revealed the effective components and molecular mechanisms of SJZD in the treatment of CRC, and we used molecular docking and experiment for preliminary verification.

Topics & Keywords

Pharmacological Effects of Natural Compounds Medicinal Plant Pharmacodynamics Research Cytokine Signaling Pathways and Interactions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Ethnopharmacology

Volume 302, Issue Pt A, pp. 115876-115876

DOI: 10.1016/j.jep.2022.115876

Field-Weighted Citation Impact: 42.29