Sex Differences in Characteristics, Outcomes, and Treatment Response With Dapagliflozin Across the Range of Ejection Fraction in Patients With Heart Failure: Insights From DAPA-HF and DELIVER

202252 citationsJournal Articlehybrid Open Access

Authors

Xiaowen Wang · Brigham and Women's Hospital

Muthiah Vaduganathan · Brigham and Women's Hospital

Brian Claggett · Brigham and Women's Hospital

Sheila M. Hegde · Brigham and Women's Hospital

Maria Pabón · Brigham and Women's Hospital

Ian J. Kulac · Brigham and Women's Hospital

Orly Vardeny

Abstract

In DAPA-HF and DELIVER, the response to dapagliflozin was similar between men and women. Sex did not modify the treatment effect of dapagliflozin across the range of ejection fraction.

Topics & Keywords

Diabetes Treatment and Management Pancreatic function and diabetes Heart Failure Treatment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 147, Issue 8, pp. 624-634

DOI: 10.1161/circulationaha.122.062832

Field-Weighted Citation Impact: 6.84