Mediation of PKM2-dependent glycolytic and non-glycolytic pathways by ENO2 in head and neck cancer development

202355 citationsJournal Articlegold Open Access

Authors

Lixia Gao · Chongqing Academy of Chinese Materia Medica

Fan Yang · Emory University

Dianyong Tang · Chongqing University of Arts and Sciences

Zhigang Xu · Chongqing University of Arts and Sciences

Yan Tang · Chongqing University of Arts and Sciences

Donglin Yang · Chongqing University of Arts and Sciences

Deping Sun

Abstract

Our work elucidates the signaling basis underlying ENO2-dependent HNSCC development, providing evidence to establish a novel ENO2-targeted therapy for treating HNSCC.

Topics & Keywords

Cancer, Hypoxia, and Metabolism RNA modifications and cancer ATP Synthase and ATPases Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 42, Issue 1, pp. 1-1

DOI: 10.1186/s13046-022-02574-0

Field-Weighted Citation Impact: 13.28