Assessing the commutability of candidate reference materials for the harmonization of neurofilament light measurements in blood

202332 citationsJournal Articlehybrid Open Access

Authors

Ulf Andréasson · Sahlgrenska University Hospital

Johan Gobom · University of Gothenburg

Vincent Delatour · Laboratoire National de Métrologie et d'Essais

Guy Auclair · European Commission

Yoav Noam · ProteinSimple (United States)

Stephen Lee · Siemens Healthcare (United States)

Jason Wen

Abstract

The results from this first commutability study on NfL in serum/plasma showed that it is feasible to create a CRM for NfL in blood and that spiking should be done using CSF rather than with recombinant human NfL protein.

Topics & Keywords

Amyotrophic Lateral Sclerosis Research Skin and Cellular Biology Research

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Clinical Chemistry and Laboratory Medicine (CCLM)

Volume 61, Issue 7, pp. 1245-1254

DOI: 10.1515/cclm-2022-1181

Field-Weighted Citation Impact: 6.63