Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma

202317 citationsJournal Articlehybrid Open Access

Authors

Javier Pérez-García · Universidad de La Laguna

Esther Herrera‐Luis · Universidad de La Laguna

Annie Li · University of California, San Francisco

Angel C. Y. Mak · University of California, San Francisco

Scott Huntsman · University of California, San Francisco

Sam S. Oh · University of California, San Francisco

Jennifer R. Elhawary

Abstract

We report novel associations of epigenetic markers with BDR in pediatric asthma and demonstrate for the first time the applicability of pharmacoepigenetics in precision medicine of respiratory diseases.

Topics & Keywords

Epigenetics and DNA Methylation Asthma and respiratory diseases Neonatal Respiratory Health Research

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Journal of Allergy and Clinical Immunology

Volume 151, Issue 6, pp. 1503-1512

DOI: 10.1016/j.jaci.2023.01.026

Field-Weighted Citation Impact: 2.62