Of mice, or men: TLR4 signaling in HIV pathogenesis

20231 citationsletterhybrid Open Access

Authors

Daniel T. Claiborne · The Wistar Institute

Abstract

A murine Tlr4null humanized mouse model offers a new tool to study mechanisms by which microbial translocation affects adaptive immune function and exacerbates HIV-1 pathogenesis.

Topics & Keywords

Immune Response and Inflammation Immune Cell Function and Interaction HIV Research and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Leukocyte Biology

Volume 113, Issue 5, pp. 415-417

DOI: 10.1093/jleuko/qiad017

Field-Weighted Citation Impact: 0.19