Mercaptopurine for the Treatment of Ulcerative Colitis: A Randomized Placebo-Controlled Trial

202324 citationsJournal Articlehybrid Open Access

Authors

Mark Löwenberg · Amsterdam University Medical Centers

Adriaan Volkers · Amsterdam University Medical Centers

Sara van Gennep · Amsterdam University Medical Centers

Aart Mookhoek · University of Bern

Nahid Montazeri · Amsterdam University Medical Centers

Esmé Clasquin · Amsterdam University Medical Centers

Marjolijn Duijvestein

Abstract

Optimized mercaptopurine treatment was superior to placebo in achieving clinical, endoscopic and histological outcomes at 1 year following corticosteroid induction treatment in UC patients. More adverse events occurred in the mercaptopurine group.

Topics & Keywords

Acute Lymphoblastic Leukemia research Inflammatory Bowel Disease Pregnancy and Medication Impact

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Crohn s and Colitis

Volume 17, Issue 7, pp. 1055-1065

DOI: 10.1093/ecco-jcc/jjad022

Field-Weighted Citation Impact: 6.92