Oral SARS-CoV-2 host responses predict the early COVID-19 disease course

20230 citationsPreprintgreen Open Access

Authors

William T. Seaman · University of North Carolina at Chapel Hill

Olive Keener · North Carolina School of Science and Mathematics

Wenwen Mei · University of North Carolina at Chapel Hill

Katie R. Mollan · University of North Carolina at Chapel Hill

Corbin D. Jones · University of North Carolina at Chapel Hill

Audrey Pettifor · University of North Carolina at Chapel Hill

Natalie M. Bowman

Abstract

Important to transmission and disease course, oral viral replication and persistence showed clear relationships with select symptoms, early Ig responses, and gender during early infection. N-antigen cross-reactivity may reflect mimicry of structurally analogous host proteins.

Topics & Keywords

SARS-CoV-2 detection and testing COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: medRxiv

DOI: 10.1101/2023.03.06.23286853