Caregiver survey in glioblastoma focused on cognitive dysfunction: development and results from a multicenter study

<b>Aim:</b> To develop a cognitive dysfunction (CD) focused questionnaire to evaluate caregiver burden in glioblastoma. <b>Materials & methods:</b> The survey was developed from stakeholder consultations and a pilot study, and disseminated at eight US academic cancer centers. Caregivers self-reported caring for an adult with glioblastoma and CD. <b>Results:</b> The 89-item survey covered demographics, CD symptoms and caregiver burden domains. Among 185 caregivers, most were white, educated females and reported memory problems as the most common CD symptom. An exposure-effect was observed, with increase in number of CD symptoms significantly associated with greater caregiver burden. <b>Conclusion:</b> This questionnaire could guide caregiver interventions and be adapted for use longitudinally, in community cancer settings, and in patients with brain metastases.