Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter‐induced lung injury

202330 citationsJournal Article

Authors

Tingting Dong · Jilin University

Xiaoye Fan · First Hospital of Jilin University

Nan Zheng · Second Affiliated Hospital of Jilin University

Kun Yan · First Hospital of Jilin University

Tianhua Hou · First Hospital of Jilin University

Liping Peng · First Hospital of Jilin University

Xinxin Ci

Abstract

Our data proposed the protective effect of Nrf2 activation on PM2.5-induced lung injury by inhibiting ferroptosis-mediated lipid peroxidation and highlight the potential of tectoridin as a PM2.5-induced lung injury treatment.

Topics & Keywords

Ferroptosis and cancer prognosis Air Quality and Health Impacts Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Pharmacology

Volume 180, Issue 19, pp. 2532-2549

DOI: 10.1111/bph.16085

Field-Weighted Citation Impact: 7.91