Search for a command to run...
“We cannot solve our problems with the same thinking we used when we created them.”–Albert Einstein“For things to reveal themselves to us, we need to be ready to abandon our views about them.”–Thich Nhat HahnCentral MessageRapid bPAB within 48 hours of birth will mitigate the reduction of systemic oxygen delivery due to circulatory maldistribution that occurs immediately during the transitional circulation in HLHS. Rapid bPAB within 48 hours of birth will mitigate the reduction of systemic oxygen delivery due to circulatory maldistribution that occurs immediately during the transitional circulation in HLHS. Since the description of hypoplastic left heart syndrome (HLHS) by Noonan and Nadas in 1958, and the seminal publication of surgical intervention by Norwood, Lang, and Hansen in 1982,1Norwood W.I. Lang P. Hansen D.D. Physiologic repair of aortic atresia-hypoplastic left heart syndrome.N Engl J Med. 1983; 308: 23-26Crossref PubMed Google Scholar outcomes have improved remarkably from a universally fatal lesion to one where there are now survivors in their fourth decade of life.2Ghanayem N.S. Allen K.R. Tabbutt S. Atz A.M. Clabby M.L. Cooper D.S. Interstage mortality after the Norwood procedure: results of the multicenter single ventricle reconstruction trial.J Thorac Cardiovasc Surg. 2012; 144: 896-906Abstract Full Text Full Text PDF PubMed Scopus (257) Google Scholar Key elements in the maturation of surgical therapies and medical management have included modifications of the original Norwood operation, including techniques for arch reconstruction and options to provide pulmonary blood flow3Newburger J.W. Sleeper L.A. Gaynor J.W. Hollenbeck-Pringle D. Frommelt P.C. Li J.S. et al.Transplant-free survival and interventions at 6 years in the SVR trial.Circulation. 2018; 137: 2246-2253Crossref PubMed Scopus (140) Google Scholar; improved anesthesia and cardiopulmonary bypass (CPB)4Goldberg C.S. Deep hypothermic circulatory arrest and regional cerebral perfusion in pediatric cardiac surgery.Prog Pediatr Cardiol. 2010; 29: 67-71Crossref Scopus (0) Google Scholar; improved understanding of the multidistribution circulation5Wernovsky G. Tweddell J.S. Physiologic Principles to Maximize Outcome in Patients With a Functionally Univentricular Heart.in: Wernovsky G. Anderson R.H. Kumar K. Mussatto K.A. Redington A.N. Tweddell J.S. Anderson’s Pediatric Cardiology. Fourth Edition. Elsevier Publishing, Philadelphia2020Google Scholar; hybrid palliation for high-risk patients6Ozturk M. d’Udekem Y. Yerebakan C. Hypoplastic left heart syndrome-pushing the limits.J Thorac Cardivoasc Surg Tech. 2022; 13: 165-166Google Scholar, 7Yerebakan C. Tongut A. Ozturk M. Ceneri N.M. d'Udekem Y. The technique of bilateral pulmonary artery banding in high-risk patients with hypoplastic left heart syndrome.Operat Tech Thorac Cardiovasc Surg. June 12, 2022; ([Epub ahead of print]. https://doi.org/10.1053/j.optechstcvs.2022.06.004)Abstract Full Text Full Text PDF Scopus (0) Google Scholar, 8Ceneri N.M. Desai M.H. Tongut A. Ozturk M. Ramakrishnan K. Staffa S.J. et al.Hybrid strategy in neonates with ductal-dependent systemic circulation and multiple risk factors.J Thorac Cardiovasc Surg. 2022; 164: 1291-1303.e6Abstract Full Text Full Text PDF PubMed Scopus (10) Google Scholar, 9Akintuerk H. Michel-Behnke I. Valeske K. Mueller M. Thul J. Bauer J. et al.Stenting of the arterial duct and banding of the pulmonary arteries: basis for combined Norwood stage I and II repair in hypoplastic left heart.Circulation. 2002; 105: 1099-1103Crossref PubMed Scopus (271) Google Scholar, 10Galantowicz M. Cheatham J.P. Phillips A. Cua C.L. Hoffman T.M. Hill S.L. et al.Hybrid approach for hypoplastic left heart syndrome: intermediate results after the learning curve.Ann Thorac Surg. 2008; 85 (discussion 2070-1): 2063-2071Abstract Full Text Full Text PDF PubMed Scopus (342) Google Scholar, 11Michel-Behnke I. Akintürk H. Schranz D. Fate of the stented arterial duct.Circulation. 2000; 102: E178Crossref PubMed Google Scholar, 12Schranz D. Bauer A. Reich B. Steinbrenner B. Recla S. Schmidt D. et al.Fifteen-year single center experience with the “Giessen Hybrid” approach for hypoplastic left heart and variants: current strategies and outcomes.Pediatr Cardiol. 2015; 36: 365-373Crossref PubMed Scopus (105) Google Scholar; a “deferred Norwood” strategy13Hoashi T. Imai K. Okuda N. Komori M. Kurosaki K. Ichikawa H. Intermediate-term outcomes of deferred Norwood strategy.Eur J Cardio Thorac Surg. 2022; 62ezac099Crossref PubMed Scopus (3) Google Scholar (bilateral pulmonary artery banding [PAB] and prostaglandin); improvements in interstage monitoring14Ghanayem N. Hoffman G. Mussatto K. Cava J. Frommelt P. Rudd N. et al.Home surveillance program prevents interstage mortality after the Norwood procedure.J Thorac Cardiovasc Surg. 2003; 126: 1367-1375Abstract Full Text Full Text PDF PubMed Scopus (301) Google Scholar,15Oster M.E. Kelleman M. McCracken C. Ohye R.G. Mahle W.T. Association of digoxin with interstage mortality: results from the pediatric heart network single ventricle reconstruction trial public use dataset.J Am Heart Assoc. 2016; 5e002566Crossref Scopus (46) Google Scholar; an interim superior cavopulmonary connection (SCPC)16Norwood W.I. Jacobs M.L. Fontan's procedure in two stages.Am J Surg. 1993; 166: 548-551Abstract Full Text PDF PubMed Scopus (115) Google Scholar; modifications of the Fontan operation17Bridges N.D. Mayer J.E. Lock J.E. Jonas R.A. Hanley F.L. Keane J.F. et al.Effect of baffle fenestration on outcome of the modified Fontan operation.Circulation. 1992; 86: 1762-1769Crossref PubMed Google Scholar, 18de Leval M.R. Kilner P. Gewillig M. Bull C. McGoon D.C. Total cavopulmonary connection: a logical alternative to atriopulmonary connection for complex Fontan operations.J Thorac Cardiovasc Surg. 1988; 96: 682-695Abstract Full Text PDF PubMed Google Scholar, 19Laks H. Ardehali A. Grant P.W. Permut L. Aharon A. Kuhn M. et al.Modification of the Fontan procedure. Superior vena cava to left pulmonary artery connection and inferior vena cava to right pulmonary artery connection with adjustable atrial septal defect.Circulation. 1995; 91: 2943-2947Crossref PubMed Google Scholar; and a better understanding of the longer-term consequences of the Fontan circulation/total cavopulmonary connection.20d'Udekem Y. Iyengar A.J. Galati J.C. Forsdick V. Weintraub R.G. Wheaton G.R. et al.Redefining expectations of long-term survival after the Fontan procedure: twenty-five years of follow-up from the entire population of Australia and New Zealand.Circulation. 2014; 130: S32-S38Crossref PubMed Scopus (416) Google Scholar, 21Dennis M. Zannino D. du Plessis K. Bullock A. Disney P.J. Radford D.J. et al.Clinical outcomes in adolescents and adults after the Fontan procedure.J Am Coll Cardiol. 2018; 71: 1009-1017Crossref PubMed Scopus (104) Google Scholar, 22Iyengar A.J. Shann F. Cochrane A.D. Brizard C.P. d’Udekem Y. The Fontan procedure in Australia: a population-based study.J Thorac Cardiovasc Surg. 2007; 134: 1353-1354Abstract Full Text Full Text PDF PubMed Scopus (0) Google Scholar Finally, although neonatal heart transplantation remains a viable surgical option, limited donor availability renders strategy a of surgical for the of the of improvements in the management and are to and for and within cardiac of procedure of the Norwood to systemic oxygen and after and the use of of have due to the during the for after birth and immediately after be that of surgical mortality by the risk of the patients the surgical With in the mortality for the Fontan Norwood during the neonatal M.L. Gaynor J.W. M. et years and Norwood survival Thorac Cardiovasc Surg. Full Text Full Text PDF PubMed Scopus Google Scholar interstage N.S. Allen K.R. Tabbutt S. Atz A.M. Clabby M.L. Cooper D.S. Interstage mortality after the Norwood procedure: results of the multicenter single ventricle reconstruction trial.J Thorac Cardiovasc Surg. 2012; 144: 896-906Abstract Full Text Full Text PDF PubMed Scopus (257) Google Scholar and Fontan and have in longer-term survival that have J.W. Sleeper L.A. Gaynor J.W. Hollenbeck-Pringle D. Frommelt P.C. Li J.S. et al.Transplant-free survival and interventions at 6 years in the SVR trial.Circulation. 2018; 137: 2246-2253Crossref PubMed Scopus (140) Google J.E. Hill K. Jacobs J.P. Kumar The of Heart on outcomes and Thorac Surg. Full Text Full Text PDF PubMed Google A.J. D.S. Galati J.C. Wheaton G.R. et Fontan procedure in Australia and New hypoplastic left heart syndrome and J Cardio Thorac Surg. 2014; (discussion PubMed Scopus Google R.G. Sleeper L.A. L. J.W. M. et of in the Norwood procedure for Engl J Med. 2010; PubMed Scopus Google Scholar The hybrid operation, used at a procedure for at for patients at at survival at years M. outcomes with the stage procedure after an hybrid stage Thorac Cardiovasc Surg. 2016; Full Text Full Text PDF PubMed Google Scholar, C. Valeske K. H. Mueller M. Thul J. et al.Hybrid for hypoplastic left heart syndrome: Thorac Cardiovasc Surg. 2016; Full Text Full Text PDF PubMed Scopus Google Scholar, H. B. M. approach for hypoplastic left heart syndrome and variants: the of the pulmonary J Cardio Thorac Surg. 2014; PubMed Scopus Google Scholar The deferred Norwood in to have a survival of T. Imai K. Okuda N. Komori M. Kurosaki K. Ichikawa H. Intermediate-term outcomes of deferred Norwood strategy.Eur J Cardio Thorac Surg. 2022; 62ezac099Crossref PubMed Scopus (3) Google outcomes of Norwood and hybrid stage stage Mayer J.E. S. C. Jacobs J.P. The of Heart on outcomes and Thorac Surg. Full Text Full Text PDF PubMed Scopus (10) Google for the Norwood procedure and hybrid stage I included cardiac for in cardiac included with outcomes and Norwood and hybrid and to a for II P. S. G. J. et with to after stage palliation for single ventricle heart an of the Pediatric Cardiol. 2022; PubMed Scopus (0) Google S. N. C. Sleeper L.A. Cooper D.S. et for and mortality after the Norwood procedure: a from the pediatric heart network single ventricle reconstruction trial.J Thorac Cardiovasc Surg. 2012; 144: Full Text Full Text PDF PubMed Scopus Google Scholar, R.G. P. P.C. C. P. et and of in the single ventricle reconstruction trial.J Thorac Cardiovasc Surg. 2012; 144: Full Text Full Text PDF PubMed Scopus Google Scholar, Ohye R.G. M. J. C. et in for the Norwood procedure.J Thorac Cardiovasc Surg. 2012; 144: Full Text Full Text PDF PubMed Scopus Google Schmidt H. J. C. after stage I Norwood hybrid Thorac Surg. (discussion Full Text Full Text PDF PubMed Scopus Google Scholar, P. A. B. et with hypoplastic left heart syndrome cardiac a multicenter Thorac Surg. Full Text Full Text PDF PubMed Scopus Google Scholar, P. J. B. J. N. et with hypoplastic left heart syndrome stage Heart 2018; 13: PubMed Scopus (10) Google Scholar, M.L. L.A. C.S. Atz A.M. D. after the Norwood procedure.J Thorac Cardiovasc Surg. 130: Full Text Full Text PDF PubMed Scopus Google outcomes and for the Norwood procedure and hybrid stage I included cardiac for in cardiac included with P. S. G. J. et with to after stage palliation for single ventricle heart an of the Pediatric Cardiol. 2022; PubMed Scopus (0) Google D. Bauer A. Reich B. Steinbrenner B. Recla S. Schmidt D. et al.Fifteen-year single center experience with the “Giessen Hybrid” approach for hypoplastic left heart and variants: current strategies and outcomes.Pediatr Cardiol. 2015; 36: 365-373Crossref PubMed Scopus (105) Google Schmidt H. J. C. after stage I Norwood hybrid Thorac Surg. (discussion Full Text Full Text PDF PubMed Scopus Google P. A. B. et with hypoplastic left heart syndrome cardiac a multicenter Thorac Surg. Full Text Full Text PDF PubMed Scopus Google Y. H. N. A. H. K. et results of bilateral pulmonary artery banding Norwood Cardiol. 2018; PubMed Scopus Google mortality arrest at of in of Pediatric Pediatric single ventricle superior cavopulmonary for the Norwood procedure and hybrid stage I included cardiac for in cardiac included with Norwood and hybrid and to a for II in a of Pediatric Pediatric single ventricle superior cavopulmonary to the surgical mortality in cardiac of patients have with the of G. G. A. J.S. S. et interstage interstage survival after the Norwood stage J Cardio Thorac Surg. PubMed Scopus (0) Google Scholar, A. N. M. I. et of survival after the Norwood Thorac Surg. Full Text Full Text PDF PubMed Scopus Google Scholar including with of that the on the same are including consequences of to the and and to to long-term J. L. D.S. V. P. et of and to long-term outcomes Fontan Am Coll Cardiol. PubMed Scopus Google Scholar, J. Atz A.M. D.S. Gewillig M.H. et Heart Association on in the and on and and management of the and with Fontan a from the Heart Scopus Google Scholar, C.L. A. S. et with after the Fontan procedure.J Am Heart Assoc. 2022; Scopus (3) Google Scholar, A. M. S. et and in patients with heart after Fontan PubMed Scopus Google Scholar S. Hill A.M. S. et in single ventricle heart a with and Am Heart Assoc. Scopus Google Scholar, G. J. D. D. Disney P. et in Fontan Am Coll Cardiol. PubMed Scopus Google Scholar, G. D.S. L. N. T. et and modified of in patients with Fontan Am Coll Cardiol. 2022; PubMed Scopus Google Scholar C.S. Mussatto K. D. Wernovsky G. and of for with hypoplastic left heart syndrome: current and PubMed Scopus Google Scholar, W.T. Wernovsky G. outcomes in hypoplastic left heart Thorac Cardiovasc Surg Pediatr Surg Full Text Full Text PDF PubMed Google Scholar, S. J. Wernovsky G. M. et outcomes after palliation for hypoplastic left heart 2008; PubMed Scopus Google Scholar S. after a and 2012; Full Text Full Text PDF PubMed Scopus Google Scholar, Y. S. C. et and of in patients with hypoplastic left heart syndrome the hybrid stage PubMed Scopus Google Scholar, and an 2012; Full Text Full Text PDF PubMed Scopus Google Scholar, G. S. palliation in hypoplastic left heart syndrome: hybrid Norwood 2018; PubMed Scopus Google Scholar, S.L. T. M. in patients with heart with and the risk of Full Text Full Text PDF PubMed Scopus Google Scholar N. C. et in the PubMed Scopus Google Scholar N. C. et in the PubMed Scopus Google Scholar Schmidt H. J. C. after stage I Norwood hybrid Thorac Surg. (discussion Full Text Full Text PDF PubMed Scopus Google Scholar, R.H. D.J. R.H. J. et after the Fontan Thorac Cardiovasc Surg. Full Text Full Text PDF PubMed Scopus Google Scholar, J. D. M. J. et after Fontan of the J Pediatr Heart Surg. PubMed Google Scholar, J. D. A. et in with hypoplastic left heart syndrome stage palliation heart Cardiol. 2018; PubMed Scopus Google Scholar and J. Atz A.M. D.S. Gewillig M.H. et Heart Association on in the and on and and management of the and with Fontan a from the Heart Scopus Google Scholar, et pulmonary an for the reduction of in Fontan Cardiol. PubMed Scopus Google Scholar, in pediatric patients with heart Thorac Cardiovasc Surg. 2014; Full Text Full Text PDF PubMed Google Scholar the mortality and to surgical intervention for the need for a in the management of patients be the of used with a on risk for mortality and and long-term are and there are high-risk for a with where a in strategy and during the transitional circulation and during the The strategies during and themselves to and the and long-term we are a in strategy to and mortality during two bilateral during the to 48 hours of with use of and the Norwood procedure in the neonatal approach in due to a better understanding of the during the transitional with an understanding of the of the heart in the the in pulmonary and the of the the of the right ventricle the in the 48 hours of and to to N. J.E. J. right and left during J Cardiol. Full Text Full Text PDF PubMed Scopus Google Scholar, P. G. of in the left and right of the I. and of PubMed Google Scholar the after and the systemic left ventricle and a in and within the H. M. C. A. M. G. of interventions on in the Cardiol. 2002; PubMed Scopus Google Scholar the to to an with and limited to the neonatal during the transitional The and of are a at T. G. PubMed Google Scholar and of and of and for an after J. The of 2010; PubMed Scopus Google Scholar in the the of and M. J. P. H. of from to with and PubMed Scopus Google Scholar of are to there are in to the at the and at with a during the A. D. for a to neonatal PubMed Scopus Google Scholar, L. M.R. A. A. et of maturation and in neonates during the of J 2014; PubMed Scopus Google Scholar to the in in and an in arterial and blood The in the of A. The use of for in and PubMed Google Scholar, A.D. A. in neonates in J 2018; Google Scholar, A. M. H. S. in the of J Google Scholar during the after from to and to by of be of J. of in an Am 2022; PubMed Scopus (0) Google Scholar, S. J.P. of in neonates and an 36: PubMed Scopus (0) Google Scholar, F. K. A. an maturation of in and neonates by the PubMed Scopus Google Scholar the of to of the of neonatal and and to to that the neonatal are and with the in The to after birth are in the of the and and The after with the from to the of and the and in D.J. P. and in the and the in during the after 1992; Google Scholar by by and by and PubMed Scopus Google Scholar a the with and the of with of on to and by a of for and The the and the maturation during the N. B. M. Full Text Full Text PDF PubMed Scopus Google Scholar, J. C. C. B. I. et the of the in PubMed Scopus Google Scholar the the to of and of the C. of the and during PubMed Scopus Google Scholar an the of the for at after a the the and the are of the J. maturation and for 2007; PubMed Scopus Google Scholar the risk of and are at their after and are to in blood oxygen and of The and are at the of at the of the pulmonary in and of the are after and of the PubMed Google Scholar and the of that in will to the within the of and the of to PubMed Scopus Google Scholar to the of the the in pulmonary have and will be in the in in hours J.S. in the of the PubMed Google Scholar the combined cardiac from the single with the in a with a N. J. J. in cardiac in with heart 2022; PubMed Scopus (0) Google Scholar, L. S. S.J. L. et in for the of blood and oxygen in and PubMed Scopus Google Scholar to a with a heart where the and left ventricle are after the the multidistribution systemic blood the pulmonary blood G. Tweddell J.S. Physiologic Principles to Maximize Outcome in Patients With a Functionally Univentricular Heart.in: Wernovsky G. Anderson R.H. Kumar K. Mussatto K.A. Redington A.N. Tweddell J.S. Anderson’s Pediatric Cardiology. Fourth Edition. Elsevier Publishing, Philadelphia2020Google Scholar in during the of by a combined in and heart L. A. N.S. Wernovsky G. The and neonatal in hypoplastic left heart syndrome with systemic and cerebral J Cardiol. Full Text Full Text PDF PubMed Scopus (0) Google Scholar to a the and from to after birth in to a and we that be a to an in in to the in heart and the of the the of in neonates with in due to have within in H. C.L. B. et of right with for the arterial in 1993; PubMed Google Scholar and a of of the left ventricle in neonates the arterial for of the R.A. T.M. Wernovsky G. B. Mayer J.E. et arterial for of the and the neonatal Google Scholar blood to the occurs with systemic blood by and L. A. N.S. Wernovsky G. The and neonatal in hypoplastic left heart syndrome with systemic and cerebral J Cardiol. Full Text Full Text PDF PubMed Scopus (0) Google Scholar that systemic blood within 6 hours of and to about of the during the of cerebral artery and artery are with cerebral and and cerebral and blood by in the superior vena L. A. N.S. Wernovsky G. The and neonatal in hypoplastic left heart syndrome with systemic and cerebral J Cardiol. Full Text Full Text PDF PubMed Scopus (0) Google Scholar cerebral blood and oxygen delivery and cerebral oxygen during the Gaynor J.W. D.J. during in the with heart of the Pediatr 2018; PubMed Scopus Google Scholar, T. M.E. K. et cerebral from birth to in neonates with heart Thorac Cardiovasc Surg. 2018; Full Text Full Text PDF PubMed Scopus Google Scholar and to the long-term in C.S. J.W. C. F. Gaynor J.W. et outcomes for with PubMed Scopus Google Scholar, J. D. S. A. K. P. et with cardiac and 2022; Scopus Google Scholar neonates with although systemic blood immediately after the of systemic blood blood risk of and the to L. A. N.S. Wernovsky G. The and neonatal in hypoplastic left heart syndrome with systemic and cerebral J Cardiol. Full Text Full Text PDF PubMed Scopus (0) Google Scholar, G.R. P.W. Gaynor J.W. et in neonates with heart risk and 2000; PubMed Google Scholar, L. The of with hypoplastic left heart PubMed Scopus Google Scholar, A. and of the hypoplastic left heart Pediatr Cardiol. Scopus (0) Google Scholar, K. K. T. Hypoplastic left heart syndrome: of survival surgical Heart J. 137: PubMed Google Scholar the pulmonary blood in and pulmonary of interventions be to the combined cardiac to the systemic including and with and to oxygen and techniques to oxygen and blood to oxygen and for systemic of interventions and of have during the a of use strategies during the neonates and a cardiac for at to hours after G. D. Jonas R.A. Mayer J.E. Hanley F.L. et and after the arterial in neonates and of cardiopulmonary bypass and circulatory 1995; PubMed Google Scholar, T.M. Wernovsky G. Atz A.M. A. J.F. et use of after cardiac in Heart J. 2002; PubMed Scopus (140) Google Scholar to the due to of the to be after in patients with stage Norwood the of are a to risk of Gaynor J.W. J. S. et by are after neonatal cardiac Thorac Cardiovasc Surg. 2015; (discussion Full Text Full Text PDF PubMed Scopus Google Scholar J. L. A. P.W. et after heart with and the use of circulatory PubMed Scopus Google Scholar J. R.A. Wernovsky G. et in heart for heart Thorac Surg. Full Text Full Text PDF PubMed Scopus Google Scholar, A.J. C.S. L.A. et in with cardiac from the pediatric 2015; Full Text Full Text PDF PubMed Google Scholar and A.J. C.S. L.A. et in with cardiac from the pediatric 2015; Full Text Full Text PDF PubMed Google in a to the surgical mortality in the entire of heart a of the hybrid Norwood in the the of the Norwood with and regional cerebral perfusion hypothermic circulatory a risk to the and The Norwood procedure during the neonatal a of the systemic of on with to in the circulation with and maldistribution of G. Tweddell J.S. Physiologic Principles to Maximize Outcome in Patients With a Functionally Univentricular Heart.in: Wernovsky G. Anderson R.H. Kumar K. Mussatto K.A. Redington A.N. Tweddell J.S. Anderson’s Pediatric Cardiology. Fourth Edition. Elsevier Publishing, Philadelphia2020Google Scholar that there a of cardiac cardiac and and are after for at of the The of about be the superior cavopulmonary connection during the same in of patients and in be with bPAB within to 48 hours of and of the Norwood procedure the neonatal that bPAB will the circulatory for improved including maturation and R.A. T.M. Wernovsky G. B. Mayer J.E. et arterial for of the and the neonatal Google Scholar, C. Jonas R.A. Wernovsky G. Rapid arterial of left after pulmonary artery banding in with of the PubMed Scopus Google Scholar C. Y. M. and right the hybrid palliation strategy for hypoplastic left heart syndrome and J Pediatr Heart Surg. PubMed Google Scholar and heart during the neonatal and blood in in the PubMed Google Scholar will the of and J. D. A. P. P. et after cardiac on of and Thorac Surg. Full Text Full Text PDF PubMed Scopus (0) Google Scholar a risk of after M. N. K.R. et of risk in after cardiopulmonary bypass in the of hypothermic cardiac 2022; 36: PubMed Scopus Google Scholar improved an in blood and blood in in the PubMed Google Scholar and improved maturation of the and with bPAB in a hybrid with an of to 6 a stage the bPAB for a deferred Norwood be a of to 6 of banding bPAB approach to circulatory maldistribution in of the the on the of of during the transitional L. A. N.S. Wernovsky G. The and neonatal in hypoplastic left heart syndrome with systemic and cerebral J Cardiol. Full Text Full Text PDF PubMed Scopus (0) Google Scholar we that of the pulmonary strategy the in systemic blood and oxygen delivery to the and bPAB will provide systemic oxygen delivery during the that to the and the a and for the that approach will the of interventions in of and that the of bPAB in a population of neonates with be with survival and D. Bauer A. Reich B. Steinbrenner B. Recla S. Schmidt D. et al.Fifteen-year single center experience with the “Giessen Hybrid” approach for hypoplastic left heart and variants: current strategies and outcomes.Pediatr Cardiol. 2015; 36: 365-373Crossref PubMed Scopus (105) Google Scholar to that banding will have with the from a Norwood procedure in the of the Norwood procedure with and the neonatal the to in a with and a with a deferred Norwood bPAB at a of and N. M. Y. Y. M. H. et bilateral pulmonary artery banding stage Norwood a viable Thorac Cardiovasc Surg. 2014; Full Text Full Text PDF PubMed Google Scholar and after the deferred Norwood with a Norwood during the neonatal Finally, to the hybrid approach deferred Norwood approach be are The be on experience approach at and there are a of to be in the Norwood by a in a surgical in to the be the cerebral and be on with aortic there are the from and Norwood will be the consequences of to 6 in of are be that an to the same we be the use of approach the Norwood to be a the of the on and need to be need and of and and after the Norwood procedure on a population are The current and long-term results of surgical intervention for although in the and better with to and long-term survival and of for patients and their the we about the circulation in the consequences of the transitional and the at we that our of bPAB within 48 hours and a Norwood procedure are the in the management of HLHS.