Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery

2023110 citationsJournal Articlegreen Open Access

Authors

Luis D. Pacheco · Memorial Hermann

Rebecca G. Clifton · Memorial Hermann

George R. Saade · Memorial Hermann

Steven J. Weiner · Memorial Hermann

Samuel Parry · Memorial Hermann

John M. Thorp · University of North Carolina at Chapel Hill

Monica Longo ·

Abstract

Prophylactic use of tranexamic acid during cesarean delivery did not lead to a significantly lower risk of a composite outcome of maternal death or blood transfusion than placebo. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development; ClinicalTrials.gov number, NCT03364491.).

Topics & Keywords

Blood transfusion and management Maternal and fetal healthcare Trauma, Hemostasis, Coagulopathy, Resuscitation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 388, Issue 15, pp. 1365-1375

DOI: 10.1056/nejmoa2207419

Field-Weighted Citation Impact: 11.74