Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first‐line therapies

202310 citationsJournal Articlegreen Open Access

Authors

Heather E. Olson · Boston Children's Hospital

Scott Demarest · University of Colorado Anschutz Medical Campus

Elia Pestana‐Knight · Cleveland Clinic

Ahsan N. Moosa · Cleveland Clinic

Xiaoming Zhang · Cleveland Clinic

José R. Pérez‐Pérez · Cleveland Clinic

Judy Weisenberg ·

Abstract

Compared to the broad group of infants with ES, children with ES in the setting of CDD often experience longer lead time to treatment and respond poorly to standard treatments. Development of alternative treatments for ES in CDD is needed.

Topics & Keywords

Genetics and Neurodevelopmental Disorders Tuberous Sclerosis Complex Research Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Epilepsia

Volume 64, Issue 7, pp. 1821-1832

DOI: 10.1111/epi.17630

Field-Weighted Citation Impact: 3.15