Responsiveness to Vedolizumab Therapy in Ulcerative Colitis is Associated With Alterations in Immune Cell-Cell Communications

202310 citationsJournal Articlegreen Open Access

Authors

Paul Wei‐Che Hsu · University of California San Diego

Eunice J. Choi · University of California San Diego

Shefali A. Patel · University of California San Diego

William H. Wong · University of California San Diego

Jocelyn G. Olvera · University of California San Diego

Priscilla Yao · University of California San Diego

Yi Chia Liu

Abstract

Overall, our results indicate that efforts to elucidate cell-cell communications among immune and nonimmune cell types may increase the mechanistic understanding of current and investigational therapies for IBD.

Topics & Keywords

IL-33, ST2, and ILC Pathways Single-cell and spatial transcriptomics Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Inflammatory Bowel Diseases

Volume 29, Issue 10, pp. 1602-1612

DOI: 10.1093/ibd/izad084

Field-Weighted Citation Impact: 1.64