Serum Insulin-like Factor 3, Testosterone, and LH in Experimental and Therapeutic Testicular Suppression

20237 citationsJournal Article

Authors

Jakob Albrethsen · University of Copenhagen

Peter Busch Østergren · Gentofte Hospital

Pernille Badsberg Norup · Copenhagen University Hospital

Jens Sønksen · Gentofte Hospital

Mikkel Fode · Gentofte Hospital

Caroline Kistorp · University of Copenhagen

Nikolai Baastrup Nordsborg

Abstract

INSL3 resembles testosterone as a sensitive marker of testicular suppression and reflects Leydig cell function, also during exposure to exogenous testosterone. Serum INSL3 measurements may complement testosterone as a Leydig cell marker in male reproductive disorders, during therapeutic testicular suppression as well as in surveillance of illicit use of androgens.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 108, Issue 11, pp. 2834-2839

DOI: 10.1210/clinem/dgad291

Field-Weighted Citation Impact: 1.77