Blood tau‐PT217 contributes to the anesthesia/surgery‐induced delirium‐like behavior in aged mice

202344 citationsJournal Articlebronze Open Access

Authors

Jing Lu · Harvard University

Feng Liang · Harvard University

Ping Bai · Harvard University

Chenghao Liu · Harvard University

Miao Xu · Harvard University

Zhengwang Sun · Harvard University

Wenjie Tian · Harvard University

Abstract

Acute increases in blood tau-PT217 may contribute to brain dysfunction and postoperative delirium. Targeting B cells or mitochondrial function may have therapeutic potential for preventing or treating these conditions.

Topics & Keywords

Intensive Care Unit Cognitive Disorders Anesthesia and Neurotoxicity Research Neuroscience and Neuropharmacology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alzheimer s & Dementia

Volume 19, Issue 9, pp. 4110-4126

DOI: 10.1002/alz.13118

Field-Weighted Citation Impact: 9.44