Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest

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Authors

Glenn M. Eastwood · Intensive Care Society

Alistair Nichol · University College Dublin

Carol Hodgson · The Alfred Hospital

Rachael Parke · University of Auckland

Shay McGuinness · University College Dublin

Niklas Nielsen · Lund University

Stephen Bernard ·

Abstract

In patients with coma who were resuscitated after out-of-hospital cardiac arrest, targeted mild hypercapnia did not lead to better neurologic outcomes at 6 months than targeted normocapnia. (Funded by the National Health and Medical Research Council of Australia and others; TAME ClinicalTrials.gov number, NCT03114033.).

Topics & Keywords

Cardiac Arrest and Resuscitation Intensive Care Unit Cognitive Disorders Respiratory Support and Mechanisms

Publication Details

Published in: New England Journal of Medicine

Volume 389, Issue 1, pp. 45-57

DOI: 10.1056/nejmoa2214552

Field-Weighted Citation Impact: 44.24

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Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest

Authors

Abstract

Topics & Keywords

Publication Details