Uncovering the impact of SARS-CoV2 spike protein variants on human receptors: A molecular dynamics docking and simulation approach

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Authors

Muhammad Zaheer · University of the Punjab

Nouman Ali · University of Central Punjab

Hasnain Javed · University of the Punjab

Abstract

These variants in Pakistani strains of SARS-CoV-2 are increasing the stability of spike protein with human receptors. These findings provide insight into how the SARS-CoV-2 virus evolves and adapts to human hosts. This information may help develop strategies to control the virus's spread and develop effective treatments and vaccines in the future.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research vaccines and immunoinformatics approaches

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Infection and Public Health

Volume 16, Issue 10, pp. 1544-1555

DOI: 10.1016/j.jiph.2023.07.011

Field-Weighted Citation Impact: 4.67