COVID-19 and Preeclampsia: A Systematic Review of Pathophysiological Interactions

20239 citationsReviewdiamond Open Access

Authors

Maria Isabel do Nascimento · Universidade Federal Fluminense

Alfredo de Almeida Cunha · Universidade do Estado do Rio de Janeiro

N. Netto · Universidade Federal Fluminense

Raphael Alves dos Santos · Universidade Federal Fluminense

Rodrigo Roberto Barroso · Universidade Federal Fluminense

Thiago Rodrigues de Carvalho Alves · Universidade Federal do Rio de Janeiro

Wender Emiliano Soares

Abstract

The studies retrieved in this review suggest that there is a possible overlap of pathophysiological interactions between COVID-19 and preeclampsia, which mainly involve ACE-2 and endothelial dysfunction. Given that preeclampsia courses with progressive clinical and laboratory alterations, a highly quality prenatal care may be able to detect specific clinical and laboratory parameters to differentiate a true preeclampsia superimposed by covid-19, as well as cases with hypertensive manifestations resulting from viral infection.

Topics & Keywords

COVID-19 Impact on Reproduction Pregnancy and preeclampsia studies Gestational Diabetes Research and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Revista Brasileira Ginecologia e Obstetrícia

Volume 45, Issue 06, pp. 347-355

DOI: 10.1055/s-0043-1770091

Field-Weighted Citation Impact: 2.66