Comparative effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in immunocompromised individuals: a systematic review and meta-analysis using the GRADE framework

202337 citationsReviewgold Open Access

Authors

Xuan Wang

Katrin Haeussler

Anne Spellman · Health Data Research UK

Leslie E. Phillips · Model Driven Solutions (United States)

Allison Ramiller · Model Driven Solutions (United States)

Mary T. Bausch-Jurken · Moderna Therapeutics (United States)

Pawana Sharma · Imperial Consultants

Anna Krivelyova

Abstract

This GRADE meta-analysis based on a large number of consistent observational studies showed that the mRNA-1273 COVID-19 vaccine is associated with improved clinical effectiveness in IC populations compared with BNT162b2.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research Vaccine Coverage and Hesitancy COVID-19 Clinical Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 14, pp. 1204831-1204831

DOI: 10.3389/fimmu.2023.1204831

Field-Weighted Citation Impact: 7.33