Study of Combined Effect of Bacteriophage vB3530 and Chlorhexidine on the Inactivation of Pseudomonas aeruginosa

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Authors

Yan Liu · First Affiliated Hospital of Wenzhou Medical University

Yining Zhao · First Affiliated Hospital of Wenzhou Medical University

Changrui Qian · Wenzhou Medical University

Zeyu Huang · First Affiliated Hospital of Wenzhou Medical University

Luozhu Feng · Wenzhou Medical University

Lijiang Chen · Wenzhou Medical University

Zhuocheng Yao

Abstract

In this study, the combination of bacteriophage vB3530 and CHG presented a combined inactivation effect to CHG-tolerant P. aeruginosa and reduced the emergence of strains resistant to CHG and phage. This study demonstrated the potential of bacteriophage as adjuvants to traditional disinfectants. The use of bacteriophage in combination with commercial disinfectants might be a promising method for controlling the spread of bacteria in hospitals.

Topics & Keywords

Bacteriophages and microbial interactions Biosensors and Analytical Detection Antimicrobial agents and applications

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: BMC Microbiology

Volume 23, Issue 1, pp. 256-256

DOI: 10.1186/s12866-023-02976-w

Field-Weighted Citation Impact: 5.44