Comparison of two corticosteroid regimens on brain volumetrics in patients with Duchenne muscular dystrophy

20238 citationsJournal Articlegold Open Access

Authors

Sam Geuens · KU Leuven

Jeroen Van Dessel · KU Leuven

Rosanne Govaarts · Leiden University Medical Center

Nadine A. Ikelaar · Leiden University Medical Center

Onno C. Meijer · Leiden University Medical Center

Hermien E. Kan · Leiden University Medical Center

E. Niks ·

Abstract

Volumetric differences in the brain are considered part of the DMD phenotype. This study suggests an additional impact of corticosteroid treatment showing a contrast between pronounced alterations seen in patients receiving daily corticosteroid treatment and more subtle differences in those treated intermittently.

Topics & Keywords

Muscle Physiology and Disorders Transcranial Magnetic Stimulation Studies Genetic Neurodegenerative Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Clinical and Translational Neurology

Volume 10, Issue 12, pp. 2324-2333

DOI: 10.1002/acn3.51922

Field-Weighted Citation Impact: 1.23