A Targeted Approach for Evaluating DUX4-Regulated Proteins as Potential Serum Biomarkers for Facioscapulohumeral Muscular Dystrophy Using Immunoassay Proteomics

20233 citationsJournal Articlebronze Open Access

Authors

Amy E. Campbell · University of Colorado Anschutz Medical Campus

Oliver D. King · University of Massachusetts Chan Medical School

Rabi Tawil · University of Rochester Medical Center

Sujatha Jagannathan · University of Colorado Anschutz Medical Campus

Abstract

ALPP, as measured with the Olink Proteomics platform, is not a promising FSHD serum biomarker candidate but could be utilized to evaluate DUX4 activity in discovery research efforts.

Topics & Keywords

Muscle Physiology and Disorders RNA modifications and cancer RNA Research and Splicing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Neuromuscular Diseases

Volume 10, Issue 6, pp. 1031-1040

DOI: 10.3233/jnd-221636

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