Safety and efficacy of human ESC-derived corneal endothelial cells for corneal endothelial dysfunction

20237 citationsJournal Articlegold Open Access

Authors

Juan Yu · University of Chinese Academy of Sciences

N.S. Yu · Center for Excellence in Molecular Cell Science

Yao Tian · University of Chinese Academy of Sciences

Yifan Fang · First Affiliated Hospital of Chinese PLA General Hospital

Bin An · Chinese Academy of Sciences

Guihai Feng · Chinese National Academy of Arts

Jun Wu

Abstract

Our work provides an efficient approach for generating iCECs and demonstrates the safety and efficacy of iCECs in disease modeling. Therefore, clinical-grade iCECs are a reliable source for future clinical treatment of corneal endothelial dysfunction.

Topics & Keywords

Corneal Surgery and Treatments Corneal surgery and disorders Developmental Biology and Gene Regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cell & Bioscience

Volume 13, Issue 1, pp. 201-201

DOI: 10.1186/s13578-023-01145-w

Field-Weighted Citation Impact: 1.62