Elevated monocyte HLA-DR in pediatric secondary hemophagocytic lymphohistiocytosis: a retrospective study

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Authors

S. Raimbault · Hôpital Femme Mère Enfant

Guillaume Monneret · Hôpital Edouard Herriot

Morgane Gossez · Hospices Civils de Lyon

Fabienne Venet · Hospices Civils de Lyon

Alexandre Bélot · Université Claude Bernard Lyon 1

Franck Zekre · Biologie, ingénierie et imagerie pour l'Ophtalmologie

Solene Remy

Abstract

In this small series, mHLA-DR was systematically elevated in patients with sHLH. Elevated mHLA-DR could contribute to sHLH diagnosis and help earlier distinction with septic shock.

Topics & Keywords

Autoimmune and Inflammatory Disorders Research Immune Cell Function and Interaction Adolescent and Pediatric Healthcare

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Immunology

Volume 14, pp. 1286749-1286749

DOI: 10.3389/fimmu.2023.1286749

Field-Weighted Citation Impact: 0.30