Pharmacokinetics of Diazepam Buccal Film in Adult Patients with Epilepsy: Comparison with Diazepam Rectal Gel (4437)

20202 citationsJournal Article

Authors

Michael A. Rogawski · University of California, Davis

Allen H. Heller

S. Farrow · Clinical Research Center of Nevada

Cassie Jung · Aquestive (United States)

Pavel Klein · Mid Atlantic Epilepsy and Sleep Center

Sylvie Boudreault · Syneos Health (United States)

Gary Slatko · Aquestive (United States)

Abstract

To assess the pharmacokinetics (PK) of diazepam buccal film (DBF) in adults with epilepsy (weight-based regimen; 12.5–17.5 mg) versus diazepam rectal gel (DRG; FDA-approved weight-based regimen; 12.5–20 mg).

Topics & Keywords

Epilepsy research and treatment Gastroesophageal reflux and treatments Advanced Drug Delivery Systems

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 94, Issue 15_supplement

DOI: 10.1212/wnl.94.15_supplement.4437

Field-Weighted Citation Impact: 0.15