A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment

20236 citationsJournal Articlehybrid Open Access

Authors

Cristina Gallego-Fábrega · Hospital de Sant Pau

Gerard Temprano‐Sagrera · Hospital de Sant Pau

Jara Cárcel‐Márquez · Hospital de Sant Pau

Elena Muiño · Hospital de Sant Pau

Natàlia Cullell · Hospital de Sant Pau

Miquel Lledós · Hospital de Sant Pau

Laia Llucià‐Carol ·

Abstract

We identified 4 shared loci between hemostatic factors and HT after r-tPA treatment, suggesting common regulatory mechanisms between fibrinogen and VWF levels and HT. Further research to determine a possible mediating effect of fibrinogen on HT risk is needed.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Thrombosis and Haemostasis

Volume 22, Issue 4, pp. 936-950

DOI: 10.1016/j.jtha.2023.11.027

Field-Weighted Citation Impact: 0.93