Topical Application of Skin Biome Care Regimen Containing Live Cultures and Ferments of <i>Cutibacterium acnes defendens</i> strain <i>XYCM42</i> and the Impact on Clinical Outcomes Following Microneedle-induced Skin Remodeling.

Integrating a microbiome-optimized, probiotic <i>XYCM42</i>-based regimen with microneedling demonstrated a high safety profile and enhanced treatment outcomes. These findings mark a milestone in aesthetic dermatology, supporting innovative microbiome-based approaches to improve skin health and aesthetics.