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Background: Postpartum women are at high risk of severe complications accompanied with COVID-19 due to the anatomical and physiological changes occurring during pregnancy and continue postpartum. Aim of the study: was to assess knowledge level of postpartum women towards COVID-19. Subjects and methods; Study design: Descriptive study. Setting: The study was conducted at the Obstetrics (postnatal unit) building at Zagazig University Hospital. Study subjects: A convenient sample of 181 postpartum women collected within 6 months. Tools of data collection: Two tools were used; Structured interview questionnaire and women knowledge towards COVID 19 questionnaire. Results: The mean age of the studied women was 30.6±4.7 years. Almost half of them had secondary education, less than two thirds of them were from urban areas. Concerning occupation and income level, less than two thirds were housewives and almost half of them had low income. As for obstetric history, less than half of women delivered two times and the vast majority had no previous obstetric complications. Conclusion: According to the present study findings, it can be concluded that the majority of the studied women had adequate level of knowledge, while less than one fifth of them had inadequate knowledge towards COVID-19. Recommendations: Health education interventions should specifically target postpartum women who may be at increased risk of contracting COVID-19.