Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction

202456 citationsJournal Articlegold Open Access

Authors

Art Schuermans · Massachusetts General Hospital

Michael C. Honigberg · Broad Institute

Laura M. Raffield · University of North Carolina at Chapel Hill

Bing Yu · The University of Texas Health Science Center at Houston

Mary B. Roberts · Brown University

Charles Kooperberg · Fred Hutch Cancer Center

Pinkal Desai

Abstract

In this cohort study, TET2 CHIP was an independent risk factor associated with incident HFpEF. This finding may have implications for the prevention and management of HFpEF, including development of targeted therapies.

Topics & Keywords

Acute Myeloid Leukemia Research Epigenetics and DNA Methylation Genomics and Rare Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Network Open

Volume 7, Issue 1, pp. e2353244-e2353244

DOI: 10.1001/jamanetworkopen.2023.53244

Field-Weighted Citation Impact: 26.14