Analytical and Functional Similarity of Aflibercept Biosimilar ABP 938 with Aflibercept Reference Product

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Authors

Neung‐Seon Seo · Amgen (United States)

Xiaoyan Guan · Amgen (United States)

Tian Wang · Amgen (United States)

Hyo S. Helen Chung · Amgen (United States)

Mats Wikström · Amgen (United States)

Rupa Padaki · Amgen (United States)

Kevin Kalenian ·

Abstract

ABP 938 was structurally and functionally similar to aflibercept RP. Since aflibercept RP sourced from the US and EU were analytically similar, this allows for the development of a scientific bridge such that a single-source RP can be used in nonclinical and clinical studies.

Topics & Keywords

Retinal Diseases and Treatments Glaucoma and retinal disorders Complement system in diseases

Publication Details

Published in: Ophthalmology and Therapy

Volume 13, Issue 5, pp. 1303-1320

DOI: 10.1007/s40123-024-00914-1

Field-Weighted Citation Impact: 2.20

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Analytical and Functional Similarity of Aflibercept Biosimilar ABP 938 with Aflibercept Reference Product

Authors

Abstract

Topics & Keywords

Publication Details