White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition

202414 citationsJournal Articlegold Open Access

Authors

Dario Bachmann · University of Zurich

Bettina von Rickenbach

Andreas Buchmann · University of Zurich

Martin Hüllner · University of Zurich

Isabelle Zuber · University of Zurich

Sandro Studer · University of Zurich

Antje Saake · University of Zurich

Abstract

Our study underscores the significance of understanding the regional distribution patterns of WMHs and the valuable insights that risk factors can offer regarding their underlying causes. Moreover, patterns of hyperintensities in periventricular regions and deep gray matter structures may have more pronounced cognitive implications, especially when amyloid pathology is also present.

Topics & Keywords

Dementia and Cognitive Impairment Research Neurological Disease Mechanisms and Treatments Frailty in Older Adults

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Alzheimer s Research & Therapy

Volume 16, Issue 1, pp. 67-67

DOI: 10.1186/s13195-024-01435-6

Field-Weighted Citation Impact: 5.40