Exagamglogene Autotemcel for Severe Sickle Cell Disease

2024328 citationsJournal Article

Authors

Haydar Frangoul · University of Illinois Chicago

Franco Locatelli · University of Illinois Chicago

Akshay Sharma · University of Illinois Chicago

Monica Bhatia · University of Illinois Chicago

Markus Y. Mapara · University of Illinois Chicago

Lyndsay Molinari · University of Illinois Chicago

Donna A. Wall

Abstract

Treatment with exa-cel eliminated vaso-occlusive crises in 97% of patients with sickle cell disease for a period of 12 months or more. (CLIMB SCD-121; ClinicalTrials.gov number, NCT03745287.).

Topics & Keywords

Hemoglobinopathies and Related Disorders Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: New England Journal of Medicine

Volume 390, Issue 18, pp. 1649-1662

DOI: 10.1056/nejmoa2309676

Field-Weighted Citation Impact: 141.81