HIV/HBV coinfection remodels the immune landscape and natural killer cell ADCC functional responses

20248 citationsJournal Articlegreen Open Access

Authors

Bo Sun · University of Oxford

Kelly da Costa · University College London

Aljawharah Alrubayyi · University of Oxford

Jonida Kokiçi · University College London

Natasha Fisher-Pearson · University of Oxford

Noshin Hussain · University College London

Stefano D’Anna ·

Abstract

This study provides new insights into the differential signature and functional profile of NK cells in HBV and HIV/HBV coinfection, highlighting pathways that can be manipulated to tailor NK cell-focused approaches to advance HBV cure strategies in different patient groups.

Topics & Keywords

Immune Cell Function and Interaction HIV Research and Treatment Cytomegalovirus and herpesvirus research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 80, Issue 3, pp. 649-663

DOI: 10.1097/hep.0000000000000877

Field-Weighted Citation Impact: 1.92