Necrotizing enterocolitis: a potential protective role for intestinal alkaline phosphatase as lipopolysaccharide detoxifying enzyme

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Authors

Raquel Dos Santos Martins · University Medical Center Groningen

Jan B.F. Hulscher · University of Groningen

Elisabeth M. W. Kooi · University Medical Center Groningen

Klaas Poelstra · University of Groningen

Abstract

This study suggests a significantly lower IAP level in resection specimens of NEC patients compared to controls. This lower IAP activity suggests a potential role of IAP as a protective agent in the gut, which needs further confirmation in larger cohorts.

Topics & Keywords

Infant Nutrition and Health Congenital Anomalies and Fetal Surgery Viral gastroenteritis research and epidemiology

Publication Details

Published in: Frontiers in Pediatrics

Volume 12, pp. 1401090-1401090

DOI: 10.3389/fped.2024.1401090

Field-Weighted Citation Impact: 0.65

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Necrotizing enterocolitis: a potential protective role for intestinal alkaline phosphatase as lipopolysaccharide detoxifying enzyme

Authors

Abstract

Topics & Keywords

Publication Details