Validation of an Automated, End-to-End Metagenomic Sequencing Assay for Agnostic Detection of Respiratory Viruses

202411 citationsJournal Articlehybrid Open Access

Authors

Nick P.G. Gauthier · University of British Columbia

Wilson Chan · University of British Columbia

Kerstin Locher · University of British Columbia

Duane E. Smailus · Canada's Michael Smith Genome Sciences Centre

Robin Coope · Canada's Michael Smith Genome Sciences Centre

Marthe Charles · University of British Columbia

Agatha N. Jassem

Abstract

This study report outlines the diagnostic performance and feasibility of mNGS for respiratory viral diagnostics, infection control, and public health surveillance. We addressed translational barriers to widespread mNGS adoption.

Topics & Keywords

Respiratory viral infections research Genomics and Phylogenetic Studies Bacteriophages and microbial interactions

Publication Details

Published in: The Journal of Infectious Diseases

Volume 230, Issue 6, pp. e1245-e1253

DOI: 10.1093/infdis/jiae226

Field-Weighted Citation Impact: 4.34

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Validation of an Automated, End-to-End Metagenomic Sequencing Assay for Agnostic Detection of Respiratory Viruses

Authors

Abstract

Topics & Keywords

Publication Details