Aortic Injury Induced by Benzo(a)pyrene and Atherogenic Diet Increased Hepatic FGF21 Expression in C57BL/6J Mice

20242 citationsJournal Articlehybrid Open Access

Authors

Farzane Shanehbandpour-Tabari · Babol University of Medical Sciences

Fatemeh Gholamnataj · Babol University of Medical Sciences

Nahid Neamati · Babol University of Medical Sciences

Ebrahim Zabihi · Babol University of Medical Sciences

Farideh Feizi · Babol University of Medical Sciences

Hadi Parsian · Babol University of Medical Sciences

Abstract

Our findings revealed that BaP increases the expression of endogenous FGF21 in treated animals as a compensatory response to protect the heart from atherosclerosis induced by BaP and AtD.

Topics & Keywords

Fibroblast Growth Factor Research Kruppel-like factors research Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Iranian journal of pharmaceutical research

Volume 23, Issue 1, pp. e142903-e142903

DOI: 10.5812/ijpr-142903

Field-Weighted Citation Impact: 0.49