Genetic profiles of oligometastatic non-small-cell lung cancer and corresponding brain metastases

20242 citationsJournal Articlehybrid Open Access

Authors

Raphael S. Werner · University Hospital of Zurich

Markus Rechsteiner · University Hospital of Zurich

Holger Moch · University Hospital of Zurich

Alessandra Curioni‐Fontecedro · University Hospital of Zurich

Michael Weller · University of Zurich

Tobias Weiß · University of Zurich

Luca Regli

Abstract

In oligometastatic NSCLC, BM retain the main genetic alterations of the primary tumours. Patients may profit from targeted inhibition of mutated KRAS. Additional private genetic alterations in the BM are dismal.

Topics & Keywords

Lung Cancer Treatments and Mutations Lung Cancer Research Studies Brain Metastases and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Journal of Cardio-Thoracic Surgery

Volume 65, Issue 6

DOI: 10.1093/ejcts/ezae217

Field-Weighted Citation Impact: 0.84