Efficacy of the Maxillary Anterior Segmental Distraction Osteogenesis in Patients With Cleft Lip and Palate: A Systematic Review and Meta-Analysis

eview question / Objective To provide evidence and reference regarding the Efficacy of the Maxillary Anterior Segmental Distraction Osteogenesis in Patients With Cleft Lip and Palate.Condition being studied Maxillary hypoplasia is a more common symptom in patients with cleft lip and palate.In addition to this, they also show anterior or posterior teeth crossbite, severe dental crowding, and a concave face due to maxillary hypoplasia.Collapsed dental arch due to alveolar cleft and speech disorders due to velopharyngeal insufficiency.These clinical symptoms seriously affect the oral function, facial aesthetics, speech level and psychological health of patients with cleft lip and palate.The lefort I osteotomy combined with distraction osteogenesis could lengthen the maxilla to improve maxillary hypoplasia.Since it also lengthens the soft, vascular, and neural tissues, it reduces the pulling of scarring tissues, which in turn reduces the recurrence rate and increases the extent of maxillary advancement. METHODS Search strategyWe searched relevant studies published before February 18, 2024 in Medline (via Pubmed), Embase, Web of Science, Cochrane Library, Scopus.Combinations of Mesh terms, free text words, appropriate truncations and filters were used without language restriction.The search terms were obtained by searching MEDLINE and were modified accordingly for other databases. Participant or populationCleft Lip and Palate patients with maxillary hypoplasia.Intervention Maxillary anterior segmental distraction osteogenesis with internal distractor.Comparator The study compared the maxilla, mandible, the anterior tooth position and the facial soft tissue before and after Maxillary anterior INPLASY