A microbiological and genomic perspective of globally collected <i>Escherichia coli</i> from adults hospitalized with invasive <i>E. coli</i> disease

Our results highlight the predominance of MDR O25b-ST131 E. coli isolates across diverse geographic areas. These findings provide further baseline data on the theoretical coverage of novel vaccines targeting E. coli associated with IED in older adults and their associated AMR levels.