A Validated LC-MS/MS Assay for the Quantification of Cholate Isotopes in Human Serum

20248 citationsJournal Article

Authors

Steve M. Helmke · ColdQuanta, Inc., DBA Infleqtion (United States)

Michael P. McRae · Custom Electronics (United States)

Uwe Christians · University of Colorado Denver

Touraj Shokati · ColdQuanta, Inc., DBA Infleqtion (United States)

Gregory T. Everson · ColdQuanta, Inc., DBA Infleqtion (United States)

Abstract

The method validation studies described herein established the performance characteristics in terms of accuracy, precision, analytical sensitivity, analytical specificity, reportable ranges, and reference intervals of the LC-MS/MS cholate assay and DuO test.

Topics & Keywords

Liver Disease Diagnosis and Treatment Liver Disease and Transplantation Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Applied Laboratory Medicine

Volume 9, Issue 6, pp. 1028-1039

DOI: 10.1093/jalm/jfae094

Field-Weighted Citation Impact: 3.28